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Literature summary extracted from

  • Taketomi, T.; Szlam, F.; Bader, S.O.; Sheppard, C.A.; Levy, J.H.; Tanaka, K.A.
    Effects of recombinant activated factor VII on thrombin-mediated feedback activation of coagulation (2008), Blood Coagul. Fibrinolysis, 19, 135-141.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.21.21 Ca2+
-
Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.21 thrombinogen + H2O Homo sapiens antifibrinolytic effect of the enzyme in relation to the activity of thrombin, regulation, overview thrombin + ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.21 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.21.21 proteolytic modification factor VII is activated by thrombin Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.21 thrombinogen + H2O
-
Homo sapiens thrombin + ?
-
?
3.4.21.21 thrombinogen + H2O antifibrinolytic effect of the enzyme in relation to the activity of thrombin, regulation, overview Homo sapiens thrombin + ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.21 activated factor VII
-
Homo sapiens
3.4.21.21 FIIa
-
Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.21.21 37
-
assay at Homo sapiens